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. 2021 Aug 21;27(31):5201–5218. doi: 10.3748/wjg.v27.i31.5201

Table 3.

Treatment options for the various disease processes that contribute to the development of dysphagia in systemic sclerosis

Disease process
Therapeutic plan
Xerostomia Drinking water more frequently[2]
Using artificial saliva as needed[2]
Using special toothpastes and mouthwashes[2]
Avoiding medications that exacerbate dry mouth[2]
Microstomia Performing exercises and massages to stretch the mouth[2]
Dental decay Planning regular follow-up with experienced dentist[2]
Concurrent myositis Frequent screening for myositis in patients with SSc and suggestive symptoms[37]
Treating concurrent myositis with immunomodulatory therapy and interventional procedures[37]
Esophageal Dysmotility Lifestyle management (taking smaller bites, chewing food thoroughly, drinking adequate water with food)[16]
GERD Medications (PPIs, H2RAs)[2,52]
Dietary modifications (avoiding acidic foods)[52]
Lifestyle modifications (avoiding meals before bedtime, elevating the head of the bed while sleeping)[2,57]
Candida esophagitis Screening for fungal esophagitis in patients with SSc and suggestive symptoms[73]
Prompt antifungal treatment[73]
Pill esophagitis Avoiding medications at high risk of causing esophagitis[79]
Screening for esophagitis in SSc patients taking culprit medications with suggestive symptoms[79]
Gastroparesis Medications (prokinetic agents)[2]
Dietary modifications of small frequent meals with fiber[2]

SSc: Systemic sclerosis; PPIs: Proton pump inhibitors; H2RAs: H2-receptor antagonists; GERD: Gastroesophageal reflux disease.