Table 2.
Kaplan-Meier and Cox proportional hazards analysis.
| Prognostic Factor | Kaplan-Meier |
Unadjusted Cox |
Adjusted Cox |
|---|---|---|---|
| Median OS p value Log Rank | p value HR (95% CI) | p value HR (95% CI) | |
| Age | |||
| 18–50 Years | 14.1 0.013 | R | |
| >50 Years | 7.6 | 0.054 7.52 (0.96–58.65) | 0.296 3.39 (0.34–33.48) |
| Karnofsky Performance status | |||
| >70 | 4.8 < 0.001 | R | |
| ≤70 | 11.9 | <0.001 13.98 (3.42–57.07) | 0.001 15.70 (3.09–79.78) |
| Edema | |||
| No | 9.3 0.027 | R | |
| Yes | 9.4 | 0.474 1.50 (0.48–4.65) | 0.898 1.09 (0.27–4.38) |
| Cell Density | |||
| Moderate | 10.3 0.492 | R | |
| High | 11.2 | 0.277 3.10 (0.40–23.94) | 0.276 3.12 (0.40–2.58) |
| IDH1 (R132H) | |||
| Negative | 12.7 0.013 | R | |
| Positive | 6.6 | 0,020 0.21 (0.05–0.78) | 0.103 0.24 (0.04–1.32) |
| HIF-1 α Expression | |||
| Negative | 10.3 0.15 | R | |
| Positive | 8.2 | 0,170 0.45 (0.14–1.40) | 0.823 1.17 (0.29–4.68) |
| Chemotherapy | |||
| Received | 12.4 0.039 | R | |
| Not Received | 6.8 | 0.062 0.32 (0.09–1.05) | 0.044 3.44 (1.03–11.48) |
R: reference, HR: Hazard Ratio.