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. 2021 Mar 28;94(7):1567–1577. doi: 10.1007/s00420-021-01652-8

Table 3.

Genotypic frequencies of RAD51/G135C and ATM/P1054R genotypes in 114 gas station workers and 115 controls

RAD51/G135C ATM/P1054R
GG GC CC CC GC GG
Group 1 59 (64.1%) 29 (31.5%) 4 (4.3%) 70 (79.5%) 18 (20.5%) 0 (0.0%)
Group 2 9 (40.9%) 10 (45.5%) 3 (13.6%) 19 (86.4%) 2 (9.1%) 1 (4.5%)
Total of workers N (%) 68 (59.6%.) 38 (33.3%) 8 (7.0%) 89 (80.9%) 20 (18.2%) 1 (0.9%)
Controls N (%) 88 (72.2%) 24 −(21.1%) 2 (1.8%) 92 (82.1%) 20 (17.9%) 0 (0.0%)
Total 156 (68.4%) 63 (27.6%) 9 (3.9%) 181 (81.5%) 40 (18.0%) 1 (0.4%)
P value P value
Hardy–Weinberg Equilibrium 0.322 0.632
Total workers × controls 0.011 0.930
Group 1 × Group 2 0.074 0.092
Polymorphisms assessment for CA detection
RAD51/G135C ATM/P1054R RAD51/G135C + ATM/P1054R
Specificity (%) 87 (76–94) 79 (68–87) 82 (75–88)
Sensitivity (%) 28 (16–43) 14 (16–43) 24 (14–35)

P value < 0.05 was considered significant

Descriptive measures: a (± b), a = average and b = standard deviation. (ab), confidence interval sample, 95%