Table 5.
Associations between genotypic frequencies of RAD51/G135C and types of chromosome alterations
| RAD51/G135C |
P value GG × GC |
P value GG × CC |
P value GG × CC + GC |
|||
|---|---|---|---|---|---|---|
| GG | GC | CC | ||||
| Translocations | ||||||
| 0 | 58 (85.3%) | 26 (68.4%) | 6 (75.0%) | 0.133 | 0.769 | 0.126 |
| 1 | 6 (8.8%) | 7 (18.4%) | 1 (12.5%) | |||
| 2 | 3 (4.4%) | 4 (10.5%) | 1 (12.5%) | |||
| 4 | 0 (0.0%) | 1 (2.6%) | 0 (0.0%) | |||
| 5 | 1 (1.5%) | 0 (0%) | 0 (0.0%) | |||
| Chr. fragments | ||||||
| 0 | 64 (94.0%) | 30 (78.9%) | 8 (100.0%) | 0.004 | 1.000 | 0.014 |
| 1 | 2 (2.9%) | 8 (21.1%) | 0 (0.0%) | |||
| 2 | 1 (1.5%) | 0 (0%) | 0 (0.0%) | |||
| 3 | 1 (1.5%) | 0 (0%) | 0 (0.0%) | |||
| Chr. Breaks | ||||||
| 0 | 63 (94.0%) | 35 (92.1%) | 6 (75.0%) | 0.787 | 0.013 | 0.245 |
| 1 | 3 (4.5%) | 3 (7.9%) | 0 (0.0%) | |||
| 2 | 0 (0.0%) | 0 (0.0%) | 2 (25.0%) | |||
| 3 | 1 (1.5%) | 0 (0.0%) | 0 (0.0%) | |||
| Deletions | ||||||
| 0 | 62 (91.2%) | 34 (91.9%) | 6 (75.0%) | 0.731 | 0.197 | 0.774 |
| 1 | 4 (5.9%) | 3 (8.1%) | 1 (12.5%) | |||
| 2 | 2 (2.9%) | 0 (0.0%) | 1 (12.5%) | |||
| Chr. Derivatives | ||||||
| 0 | 65 (95.6%) | 37 (97.4%) | 8 (100.0%) | 0.785 | 1.000 | 0.764 |
| 1 | 1 (1.5%) | 1 (2.6%) | 0 (0.0%) | |||
| 2 | 2 (2.9%) | 0 (0.0%) | 0 (0.0%) | |||
| Inversions | ||||||
| 0 | 68 (100.0%) | 36 (97.3%) | 8 (100.0%) | 0.352 | 1.000 | 0.398 |
| 1 | 0 (0.0%) | 1 (2.7%) | 0 (0.0%) | |||
| Monosomies | ||||||
| 0 | 62 (91.2%) | 36 (94.7%) | 6 (75.0%) | 1.000 | 0.248 | 1.000 |
| 1 | 4 (5.9%) | 2 (5.3%) | 1 (12.5%) | |||
| 2 | 1 (1.5%) | 0 (0.0%) | 1 (12.5%) | |||
| 5 | 1 (1.5%) | 0 (0.0%) | 0 (0.0%) | |||
| Trisomies | ||||||
| 0 | 67 (98.5%) | 37 (97.4%) | 8 (100.0%) | 1.000 | 1.000 | 1.000 |
| 1 | 1 (1.5%) | 1 (2.6%) | 0 (0.0%) | |||
P value < 0.05 was considered significant
Descriptive measures: a (± b), a = average and b = standard deviation