Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2021 Aug 24;11:17136. doi: 10.1038/s41598-021-96618-8

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

© The Author(s) 2021

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/.

PMC Copyright notice

Biventricular differences in contraction force, action potential duration and mRNA expression regulation in volume overload from aorto-caval fistula (ACF). (a) Example of action potential recording from isolated papillary muscle. (b left) Action potential duration at 90% repolarization (APD90) in RV and LV papillary muscles in controls and in ACF rats. Measurements at stimulation frequencies of 0.5, 1, 2, 3.3 and 5 Hz. *, p < 0.05, RV control vs. RV ACF; #, p < 0.05, LV control vs. LV ACF (3-way ANOVA). (b right) Maximal contraction force in RV and LV papillary muscles in control and ACF rats. (c) Relation of hypertrophy determinants to gene mRNA expression patterns in RV and LV. Note discordant relations between gene expression and ventricular pressures; concordant but steeper relation of RV compared to LV. r: Pearson´s correlation coefficient, p: p-value of correlation. The line represents linear regression with 95% confidence bands. p_slope denotes the difference between regression slopes.