Table 2.

Hemodynamic data from pressure–volume analysis.

	Control	ACF	P (t-test)	Fold-change ACF vs control
Systemic circulation
SBP, mmHg	140 ± 30	130 ± 20	0.1164	0.9
DBP, mmHg	110 ± 30	80 ± 10	< 0.0001	0.7
MBP, mmHg	130 ± 30	110 ± 20	0.0024	0.8
PP, mmHg	29 ± 6	47 ± 8	< 0.0001	1.6
SVR, mmHg.min.ml−1	1 ± 0.3	0.21 ± 0.05	< 0.0001	0.2
Left Ventricle (LV)
LV EDP, mmHg	6 ± 2	12 ± 4	< 0.0001	2.0
LV EDV, ml	0.31 ± 0.09	2.0 ± 0.5	< 0.0001	6.5
LV mass/EDV, g.ml−1	3.8 ± 0.9	1.1 ± 0.2	< 0.0001	0.3
LV ESV, ml	0.02 ± 0.01	0.5 ± 0.3	< 0.0001	25
LV max pressure, mmHg	150 ± 30	120 ± 20	< 0.0001	0.8
LV max wall stress, mmHg.ml.g−1	40 ± 10	120 ± 30	< 0.0001	3.0
Stroke work, mmHg.ml	20 ± 6	70 ± 20	< 0.0001	3.5
dP/dtmax, mmHg.s−1	10,000 ± 4000	9000 ± 3000	0.1504	0.9
PRSW, mmHg	70 ± 40	30 ± 20	0.0021	0.4
dP/dtmin, mmHg.s−1	−11,000 ± 3,000	−5000 ± 2000	< 0.0001	0.5
Tau, ms	11 ± 2	17 ± 4	< 0.0001	1.5
Right ventricle (RV)
RV EDP, mmHg	4 ± 1	6 ± 2	0.0028	1.5
RV EDV, ml	0.12 ± 0.01	0.7 ± 0.3	< 0.0001	5.8
RV mass/EDV, g.ml−1	2.4 ± 0.3	1.2 ± 0.3	< 0.0001	0.5
RV ESV, ml	0.038 ± 0.005	0.3 ± 0.2	< 0.0001	7.9
RV max pressure, mmHg	34 ± 5	46 ± 6	< 0.0001	1.4
RV max pressure—LVEDP gradient, mmHg	28 ± 6	35 ± 5	0.0023	1.3
RV max wall stress, mmHg.ml.g−1	15 ± 3	36 ± 9	< 0.0001	2.4
Stroke work, mmHg.ml	1.1 ± 0.1	7 ± 3	< 0.0001	6.4
dP/dtmax, mmHg.s−1	2200 ± 800	2900 ± 800	0.0265	1.3
PRSW, mmHg	30 ± 10	20 ± 10	0.0154	0.7
dP/dtmin, mmHg.s−1	−1600 ± 300	−1600 ± 400	0.9405	1.0
Tau, ms	20 ± 10	20 ± 10	0.9954	1.0

Values are expressed as mean ± SD.

SBP, systolic blood pressure; DBP, diastolic blood pressure; MBP, mean blood pressure; PP, pulse pressure; SCR, systemic vascular resistance; LV, left ventricle; RV, right ventricle; PRSW, preload-recruitable stroke work; EDP, enddiastolic pressure; EDV, enddiastolic volume; ESV, endsystolic volume. For other abbreviations, see text.