Table 3.

Antihyperglycemic effects of single dose aqueous leaf extract in streptozotocin-induced diabetic mice.

Groups	FBG level (mg/dl)
	0 h	1st h	2nd h	3rd h	4th h
NC	286.00 ± 12.9a3	284.00 ± 13.60Ac	277.80 ± 13.88 Ac	274.60 ± 13.80Ac	269.00 ± 14.20Ac
NOC	91.6 ± 1.16	90.00 ± 0.94	87.80 ± 1.31	84.80 ± 0.66	83.44 ± 0.87
GL5	280.60 ± 18.10Ac	239.20 ± 12.80Ac	186.60 ± 13.55 AaBa	175.00 ± 11.26 AaBb	133.00 ± 8.56 Bc
RELE100	284.00 ± 21.38Ac	266.00 ± 20.96 Ac	259.20 ± 18.02 Ac	230.00 ± 21.05 Ac	202.60 ± 29.80 Ab
RELE200	298.80 ± 24.92Ac	258.60 ± 26.70 Ac	239.20 ± 36.87 Ac	190.80 ± 27.93 AbBa	186.40 ± 26.50 AbBa
RELE400	297.80 ± 13.70a3	252.00 ± 17.42 Ac	200 ± 13.50Ab	173.20 ± 12.99AaBa	154.20 ± 12.06Ba

Each value represents mean ± S.E.M; n = 6; Analysis was performed by one way ANOVA; ^Acompared to normal control; ^Bcompared to negative control; number followed by RELE and GL indicates dose in mg/kg; ^ap < 0.05; ^bp < 0.01; ^cp < 0.001.

Abbreviations: NOC, normal control; NC, negative control; GL, glibenclamide; RELE, Rubus erlangeri leaf extract.