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. 2021 Aug 25;9:53. doi: 10.1186/s40560-021-00555-7

Table 3.

Thresholds and limits of dynamic indicators

Method Threshold Main limits

PPV (pulse pressure variation)

SVV (stroke volume variation)

12% Difficult to use in the following cases: patients with spontaneous breathing, patients with arrhythmia, patients with low tidal ventilation, and patients with low lung compliance
IVC diameter fluctuations 12% Difficult to use in the following cases: patients with spontaneous breathing, patients with arrhythmia, and patients with low lung compliance
SVC diameter fluctuations 12–40% Requires transesophageal echocardiography. Difficult to use in the following cases: patients with spontaneous breathing, patients with low tidal ventilation, and patients with low lung compliance
PLR (passive leg raising) 10%

Cardiac output is to be directly measured

Difficult to use in the following cases: patients with lower limb defects, pregnant women, patients receiving vasoactive drugs, and patients with increased intra-abdominal pressure

EEO (end-expiratory occlusion test) 5%

Difficult to use in the following cases:

non-intubated patients and patients who cannot hold their breath for more than 15 s

Low-dose fluid challenge (100 mL) 6–10% Cardiac output needs to be measured directly and accurately
Fluid challenge (500 mL) 15%

Risk of fluid overload if repeated.

Cardiac output needs to be measured directly