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. 2021 Aug 12;12(9):2557–2569. doi: 10.1007/s13300-021-01108-9

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© The Author(s) 2021

Open Access This article is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License, which permits any non-commercial use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by-nc/4.0/.

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Fig. 1 — Schematic representation of the study protocol. All 158 randomized patients had participated in the ISTERP-1 and had received the educational training in that study according to exactly the same protocol that was provided to the intervention group in the present study. CG Control group, GV glycemic variability, HbA1c glycated hemoglobin, hypos hypoglycemic episodes, IG intervention group, pts patients, SMBG self-monitoring of blood glucose, T0 baseline, T1–T6 follow-up time points, US ultrasound