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. 2021 Aug 24;11:441. doi: 10.1038/s41398-021-01566-6

Fig. 1. Experimental design and protocol.

Fig. 1

Recruited smokers came to the lab, completed the craving evaluation, and performed a cue-reactivity task in the fMRI scanner. Twenty-four hours later, they took a placebo or propranolol (40 mg) pill 1 h before they underwent two resting-state fMRI scans. Before the second scan, the participants reactivated the nicotine-associated memories by being exposed to smoking-related pictures. Again 24 h later, all of the participants completed the craving evaluation and the same cue-reactivity task in the scanner.