Table 1.

T2D and eQTL location estimates (physical coordinate, b37) associated with 50 T2D cis-NEMGs.

T2D locations p-value < 10-5						T2D locations p-value < 10-5
Chr	T2D location GWAS-Ea	T2D location GWAS-Ab	T2D location metabo-Ec	Cis-NEMG	eQTL locationd	Chr	T2D location GWAS-Ea	T2D location GWAS-Ab	T2D location metabo-Ec	Cis-NEMG	eQTL locationd
1	26006625	–	26003695	MTFR1L	25900571	12	121317223	–	121243696	ACADS	121372772
1	26006625	–	26003695	CLIC4	26002616	12	121317223	–	121243696	GATC	121186959
1	26006625	–	26003695	CLIC4	25900772	13	102408534	102452781	N/A	PCCA	102428282
1	234270220	234273988	N/A	COA6	234338743	13	111049674	111004953	111035483	NAXD	111060677
1	234270220	234273988	N/A	TOMM20	234309446	15	–	63345547	63425768	LACTB	63453484
2	–	204023399	203970861	NIF3L1	203798637	20	–	25769672	25727136	ACSS1	25740998
2	–	204023399	203970861	FLJ38973	204126463	22	33046025	33046036	N/A	PISD	33058307
2	–	204023399	203970861	MARS2	203820504	T2D locations p-value < 10-3
2	–	204023399	203970861	CPS1	204126514	2	–	194739106	194690969	COQ10B	194842026
2	227080369	–	227021099	MFF	227151692	2	–	194739106	194690969	HSPD1	194213959
3	67744088	67685265	N/A	SLC25A26	67577196	2	200305909	–	200330147	FLJ38973	200457932
3	123048537	–	123061689	CCDC58	122876198	2	200305909	–	200330147	MAIP1	200070891
3	120573472	120555505	N/A	NDUFB4	120573615	6	–	76217291	76199095	COX7A2	76466553
3	132436519	–	132429438	ACAD11	132451038	7	48732315	48812202	N/A	ABCA13	48628852
3	183260285	183210822	N/A	MCCC1	183260250	7	140349757	140367908	N/A	MRPS33	140378682
4	91942692	91950656	N/A	PDHA2	91947875	10	112924900	112866891	–	GPAM	112917454
4	104004185	–	103936988	CISD2	104141231	11	61284211	61258729	N/A	FEN1	61260634
6	112808197	112750188	N/A	GPAM	112800751	12	12633435	12621259	N/A	HEBP1	12634131
6	127539286	–	127502744	TRMT11	127479024	12	123387213	123750895	123447928	DIABLO	123386662
6	127539286	–	127502744	HINT3	127357421	12	123387213	123750895	123447928	DIABLO	123386489
10	94499812	–	94479016	Mar-05	94488072	12	123387213	123750895	123447928	ABCB9	123260234
10	104786704	–	104841790	SFXN2	104732175	12	123387213	123750895	123447928	ABCB9	123386756
11	8551677	–	8637191	CYB5R2	8667032	12	123387213	123750895	123447928	ABCB9	123386769
11	43879353	–	43879882	ALKBH3	43607412	12	123387213	123750895	123447928	COXPD7	123439939
11	65575917	–	65600493	MRPL11	65466334	12	133105848	–	133168320	PGAM5	133182753
12	56618300	–	55152275	GLS2	56628724	15	77270791	–	77310648	IDH3A	77085108
12	56618300	–	55152275	SUOX	56621500	16	9759261	–	9794698	ABAT	9799479
12	112991642	–	112988341	ALDH2	112229375	21	44327412	44352930	N/A	NDUFV3	44210786
12	106406604	106384733	N/A	MTERF2	106410234

All eQTL locations (Ŝ_eQTL) are within ±1LDU of a T2D location estimate (Ŝ_T2D) for the ^aEuropean WTCCC1 cohort (GWAS-E), ^bAfrican American NIDDK cohort (GWAS-A) and ^cEuropean WTCCC2 MetaBoChip study cohort (GWAS metabo-E) (signals with low SNP coverage, indicated by N/A, were not analyzed). ^dŜ_eQTL were generated using subcutaneous adipose gene expression for a population-based European sample from the MuTHER consortium.