Table 2.

Univariate associations of covariates with CAC > 0 and log-transformed CAC density score^a

Covariates	CAC > 0		CAC densityb,c
	Or (95% CI)	P	β (SE)	P
Age, years	1.25 (1.03, 1.52)	0.02	0.11 (0.03)	<0.0001
Race		0.001		0.38
White	----	----	----	----
Black	2.09 (1.34, 3.26)	0.001	−0.05 (0.06)	0.38
Menopausal status		0.93		0.02
Pre-/early perimenopausal	----	----	----	----
Late perimenopausal	1.05 (0.74, 1.50)	0.78	0.13 (0.08)	0.12
Postmenopausal (Natural/bilateral oophorectomy)	1.05 (0.68, 1.72)	0.75	0.17 (0.06)	0.005
BMI, kg/m2	4.48 (3.15, 6.37)	<0.0001	0.02 (0.03)	0.45
Physical activity score	0.79 (0.65, 0.96)	0.02	0.02 (0.03)	0.52
C3, mg/dL	2.03 (1.60, 2.57)	<0.0001	−0.02 (0.03)	0.58
Estradiolc	0.87 (0.73, 1.03)	0.11	−0.04 (0.03)	0.21
Alcohol consumption, n (%)		0.18		0.60
None- ≤1 drink/month	----	----	----	----
>1 drink/month	0.75 (0.49, 1.14)	0.18	0.03 (0.06)	0.60
LDL-C, mg/dL	1.23 (1.01, 1.49)	0.04	0.06 (0.03)	0.05
Triglyceridesc	1.58 (1.28, 1.96)	<0.0001	0.03 (0.02)	0.27
Systolic blood pressure, mmHg	1.94 (1.56, 2.43)	<0.0001	0.02 (0.03)	0.43
HOMA-IRc	2.67 (2.02, 3.51)	<0.0001	0.06 (0.02)	0.02
Diabetes status		0.06		0.007
No	----	----	----	----
Yes	1.99 (0.96, 4.13)	0.06	0.22 (0.08)	0.007
Smoking		0.91		0.74
Never smoker	----	----	----	----
Past smoker	1.10 (0.69, 1.73)	0.69	0.04 (0.06)	0.53
Current smoker	1.01 (0.56, 1.81)	0.98	−0.03 (0.10)	0.79
Any use of CVD medication		0.02		0.28
No	----	----	----	----
Yes	1.66 (1.09, 2.52)	0.02	0.07 (0.06)	0.28

BMI, body mass index; C3, complement protein 3; LDL-C, low-density lipoprotein cholesterol.

^aFor continuous variables, data presented per 1-SD increase.

^bAdjusted for log-transformed volume score.

^cLog-transformed.