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. 2021 Aug 11;12:707543. doi: 10.3389/fpsyt.2021.707543

Table 1.

Summary of literature reporting inflammatory cytokine changes in PTSD patients.

Research findings Sample source Index Reference
Levels of inflammatory cytokines (or cells) ↑ Plasma IL-2, IFN-γ, IL-6, TNF-α, IL-12, IL-17 (3033)
Serum TNF-α, IL-1, IL-6, IFN-γ (34)
(TNF)-α, (IFN)-γ, and CRP (35)
Serum TNF-α, IL-1β, and IL-6 (36)
Serum IL-1β (37, 38)
Serum IL-4, IL-6, IL-10, and TNF-α (32)
blood sample IL-6 (16, 3941)
serum IL-6 (42, 43)
Cerebrospinal fluid IL-6 (44)
Saliva IL-2, IFN-γ, IL-6, IL-17, CCL2 (31, 45)
Secretion of Blood cell IL-1, IL-6, TNF-α (46)
Blood cell Th1, Th17 (47)
Anti-inflammatory cytokines (or cells) ↓ Plasma TGF-β, LI-4, IL-10 (30)
Serum IL-2, IL-8 (43)
Saliva IL-4, IL-10 (31)
Blood cell Treg (46)