Table 2.
SNPs identified in Bundibugyo virus genomes from the 2012 BVD outbreak in the Democratic Republic of the Congo
Positiona | Reference base | Called base | NS mutation | Gene | Uganda 2007 | 22 P0 | 22 P1 | 37 P0 | 4 P0 | 4 P1 | 112 P0 | 74 P0 | 74 P1 | 120 P0 | 120b P0 | 116 P0 | 135 P1 | 130 P0 | 138 P1 | 122 P0 |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
577 | C | T | NP | X | X | |||||||||||||||
5,928 | T | – | X | |||||||||||||||||
6,587 | T | C | GP | X | ||||||||||||||||
6,736 | T | C | L→P | GP | ||||||||||||||||
8,096 | T | C | X | X | ||||||||||||||||
8,287 | G | A | X | |||||||||||||||||
10,031 | G | A | X | X | ||||||||||||||||
10,798 | C | T | VP24 | X | X | X | X | |||||||||||||
11,138 | T | C | X | X | X | X | ||||||||||||||
11,271 | A | G | X | X | ||||||||||||||||
14,583 | T | C | L | X | X | X | X | |||||||||||||
15,019 | T | A | L | X | X |
An “X” denotes a consensus-level change at the referred position. NS, nonsynonymous; nc, noncoding; S, synonymous.
Reference genome used for SNP analysis is the consensus sequence from the 2012 outbreak; FJ217161 is the same sequence as KR063673 and KU182911.
The genome sequence from case 120 was previously sequenced by the CDC.