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. 2021 Aug 11;8:715118. doi: 10.3389/fmed.2021.715118

Table 2.

Summary of risk factors based on different age groups.

Age ≤ 50 years Age > 50 years P-value
Total N = 118 Total N = 165
N (%) N (%)
Presence of risk factors 0.66
    None 4 (3.4) 6 (3.6)
    One 78 (66.1) 111 (67.3)
    Two 26 (22.0) 40 (24.2)
    Three or more 10 (8.5) 8 (4.8)
Type of risk factors <0.001
    OSD* 54 (45.8) 80 (50.6) 0.65
    Contact lens wear 68 (57.6) 32 (19.4) <0.001
    Immunosuppression** 9 (7.6) 43 (26.1) <0.001
    Prior corneal surgery 15 (12.7) 24 (14.5) 0.19
    Topical corticosteroids 8 (6.8) 23 (14.6) 0.06
    Trauma 10 (8.5) 15 (9.1) 0.86

OSD, Ocular surface disease.

*

Includes dry eye disease, meibomian gland disease, neurotrophic keratopathy, exposure keratopathy, previous corneal infection, corneal erosion syndrome, limbal stem cell deficiency, cicatricial conjunctivitis, band keratopathy, and bullous keratopathy.

**

Includes diabetes, use of systemic immunosuppressive drugs, malnutrition, and immunodeficiency. Significant values are in bold.