Table 3.
Summary of causative organisms of bacterial keratitis in Nottingham, UK, and their association with different risk factors.
| Total* | OSD | CL wear | CS | TC | P-value** | |
|---|---|---|---|---|---|---|
| Total N = 138 | Total N = 63 | Total N = 45 | Total N = 25 | Total N = 21 | ||
| N (%) | N (%) | N (%) | N (%) | N (%) | ||
| Gram-positive | 70 (50.7) | 38 (60.3) | 15 (33.3) | 16 (64.0) | 13 (61.9) | 0.017 |
| Staphylococci | 36 (26.1) | 20 (31.7) | 9 (20.0) | 10 (40.0) | 7 (33.3) | |
| Streptococci | 16 (11.6) | 9 (14.3) | 2 (4.4) | 4 (16.0) | 5 (23.8) | |
| Other GP | 18 (13.0) | 9 (14.3) | 4 (8.9) | 2 (8.0) | 2 (9.5) | |
| Gram-negative | 68 (49.3) | 25 (39.7) | 30 (66.7) | 9 (36.0) | 8 (38.1) | |
| Pseudomonas | 44 (31.9) | 13 (20.6) | 23 (51.1) | 6 (24.0) | 4 (19.0) | |
| Moraxella | 14 (10.1) | 8 (12.7) | 3 (6.7) | 3 (12.0) | 3 (14.3) | |
| Other GN | 10 (7.2) | 4 (6.3) | 4 (8.9) | 0 (0.0) | 1 (4.8) |
OSD, Ocular surface disease; CL, Contact lens; TC, Topical corticosteroids; CS, Previous corneal surgery; GP, Gram-positive; GN, Gram-negative.
*
The total number of organisms exceeded the total number of culture-positive cases as some cases were polymicrobial. In addition, some cases had more than one risk factor identified, and the same implicated organism was included in more than one group of risk factor.
**
Comparison of the causative organisms among different risk factors were performed. The analysis was performed at the level of Gram-positive vs. Gram-negative bacteria only. Significant values are in bold.