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. 2021 Aug 11;8:715118. doi: 10.3389/fmed.2021.715118

Table 4.

Prognostic factors for poor visual outcome [defined as corrected-distance-visual-acuity (CDVA) of <0.60 logMAR] and poor corneal healing (defined as >30 days to achieve complete healing or occurrence of corneal perforation or uncontrolled infection) in bacterial keratitis.

Parameters Poor visual outcome Poor corneal healing
Odd ratio (95% CI) P-value* Odd ratio (95% CI) P-value*
Age > 50 years 2.61 (1.24–5.47) 0.011 1.86 (1.06–3.24) 0.030
Female gender 0.81 (0.41–1.62) 0.56 1.27 (0.73–2.19) 0.40
Right eye 0.81 (0.41–1.60) 0.54 1.82 (1.05–3.16) 0.033
Epithelial defect size >3 mm 0.69 (0.19–2.50) 0.57 1.23 (0.44–3.44) 0.69
Infiltrate size > 3 mm 4.07 (1.21–13.73) 0.024 3.46 (1.24–9.70) 0.018
Central ulcer 2.13 (1.01–4.51) 0.047 1.30 (0.67–2.54) 0.43
Presence of hypopyon 0.47 (0.21–1.08) 0.08 1.02 (0.50–2.07) 0.96
Positive culture results 1.17 (0.56–2.46) 0.67 1.15 (0.63–2.10) 0.65
Presenting CDVA <0.6 29.70 (10.47–84.18) <0.001 2.22 (1.19–4.15) 0.013
*

Multivariable logistic regression analysis was performed. Significant p-values are in bold.