REAGENT or RESOURCE	SOURCE	IDENTIFIER
Antibodies
guinea pig anti-insulin	Dako; now Agilent, Santa C#lara, CA, USA	#A0546; RRID:AB_2617169
rabbit anti-glucagon		#A0565; RRID:AB_10013726
mouse anti-CD45		#M0701; RRID:AB_2314143
rabbit anti-amylase	Abcam, UK	#21156; RRID:AB_446061
rabbit anti-CD4		#133616; RRID:AB_2750883
rabbit anti-CD8		#4055; RRID:AB_304247
biotin- conjugated donkey anti-rabbit	Jackson Immuno Research, PA, USA	#711-066-152; RRID:AB_2340594
biotin- conjugated donkey anti-mouse		#715-065-150; RRID:AB_2307438
biotin- conjugated donkey anti- guinea pig		#706-066-148; RRID:AB_2340452
FITC-conjugated donkey anti-rabbit		#711-096-152; RRID:AB_2340597
FITC-conjugated donkey anti-guinea pig		#706-096-148; RRID:AB_2340454
Biological samples
Human FFPE pancreatic sections from organ donors	this paper; Kaddis et al.40 and Foulis et al.41	N/A
Chemicals, peptides, and recombinant proteins
Sudan Black	Sigma-Aldrich	#199664
Pepsin	Sigma-Aldrich	#MKCN5185
Critical commercial assays
VECTASTAIN ABC Kit	Vector Labs, USA	#PK-4000
DAB Peroxidase Substrate Kit		#SK-4100
VECTASHIELD® with 4’,6-Diamidin-2-phenylindol (DAPI)		#H-1200-10
Oligonucleotides
Sequences of probes and respective viral target regions of probes sets CVB_1, CVB_2, CVB_3	Designed with Stellaris® RNA FISH Probe Designer (Biosearch Technologies, Inc., Petaluma, CA)	This paper; See Table S3, Busse et al.17
Software and algorithms
Vision Works LS Image Acquisition and Analysis software Version 6.8	UVP BioImaging Systems, CA, USA	N/A
NIS-Elements software, v3.22.11	Nikon GmbH, Germany	N/A
GraphPad Prism v8.4.3	GraphPad	N/A
ImageJ (v.1.52(100)	NIH, USA	N/A
Other
Nikon MEA53200	Nikon GmbH, Germany	N/A