Skip to main content
. 2021 Jul 27;15:115–122. doi: 10.1016/j.jdcr.2021.07.018

Table II.

Features of acute generalized exanthematous pustulosis graded by EuroSCAR criteria4

Features Grading

Morphology
 Pustules Typical: +2; Compatible: +1; Insufficient§: 0
 Erythema Typical: +2; Compatible: +1; Insufficient: 0
 Distribution Typical: +2; Compatible: +1; Insufficient: 0
 Postpustular desquamation Yes: +1; No: 0
Course
 Mucosal involvement Yes: −2; No: 0
 Acute onset (≤10 d) Yes: 0; No: −2
 Resolution (≤15 d) Yes: 0; No: −4
 Fever (≥38 °C) Yes: +1; No: 0
 Neutrophilia (≥7000/mm3) Yes: +1; No: 0
Histopathology
 Other disease −10
 Not representative/no histology 0
 Exocytosis of neutrophils +1
 Subcorneal and/or intraepidermal nonspongiform or NOS pustules with papillary edema or subcorneal and/or intraepidermal spongiform or NOS pustules without papillary edema +2
 Spongiform subcorneal and/or intraepidermal pustules with papillary edema +3

NOS, Not otherwise specified.

Interpretation: ≤0, no acute generalized exanthematous pustulosis (AGEP); 1 to 4, possible AGEP; 5 to 7, probable AGEP; 8 to 12, definite AGEP.

Typical: Typical morphology with many nonfollicular sterile pustules arising on edematous erythema mainly in intertriginous areas.

Compatible: Not typical but not strongly suggestive of other disease.

§

Insufficient: Lesions cannot be judged (mostly because of late of the disease or poor quality of pictures).