Table 2.
Histological measurements of lung morphology.
Trait | Treatment | Highlander | Lowlander |
---|---|---|---|
Alveolar surface density (μm−1) | Control | 0.108 ± 0.003 | 0.089 ± 0.003 |
Adult hypoxia | 0.102 ± 0.002 | 0.091 ± 0.102 | |
Life-long hypoxia | 0.099 ± 0.006 | - | |
Total alveolar surface area (cm2 g−1) | Control | 31.44 ± 5.26 | 27.78 ± 2.03 |
Adult hypoxia | 35.81 ± 6.59 | 35.68 ± 2.62 | |
Life-long hypoxia | 44.18 ± 5.11 | - | |
Alveolar density (mm−2) | Control | 885 ± 51 | 770 ± 27 |
Adult hypoxia | 853 ± 86 | 661 ± 30* | |
Life-long hypoxia | 815 ± 73 | - |
Data are mean ± SEM. N as follows: five control, four adult hypoxia, and five life-long hypoxia for highlanders; six control and seven adult hypoxia for lowlanders.
Significant pairwise difference from control within a population using Holm-Sidak post-tests.