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. 2021 Aug 11;9:631904. doi: 10.3389/fcell.2021.631904

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Copyright © 2021 Zhang, Li, Fu, Wang, Wang, Meng, Wang, Yang and Chai.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Ribbon synapses in CX3CR1C^+/– and CX3CR1^{– /–} mice after noise exposure. Representative micrographs are shown for the 32-kHz region. (A) CX3CR1C^+/– mice without noise exposure show intact ribbon synapses. (B) CX3CR1C^+/– mice at 24 h after exposure show disintegrated ribbon synapses. (C) CX3CR1C^+/– mice at 8 weeks after exposure show repaired synapses. (D) CX3CR1^{– /–} mice at 8 weeks after exposure show degenerated ribbon synapses. The pre-synaptic marker CtBP2 is in red, the post-synaptic marker GluA3 is in green, and myosin VIIa is in blue. Scale = 17 mm [citing from Kaur et al. (2019)].