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. 2021 Jul 30;8(4):569–578. doi: 10.3233/JND-200624

Table 2.

Index visit costs and healthcare resource utilization for adult patients with spinal muscular atrophy by age group

Total population* Age 18–29 years Age 30–54 years Age ≥55 years p-value
(N = 446) (n = 129) (n = 163) (n = 154)
Service category
  Inpatients, n 157 47 52 58
  Outpatients, n 289 82 111 96
Resource utilization
  ED stay, n (%) 168 (38) 48 (37) 59 (36) 61 (40) 0.81
  ICU stay, n (%) 46 (29) 24 (51) 11 (21) 11 (19) < 0.001
  Inpatient length of stay, days
n 157 47 52 58
  Mean±SD 7.9±9.7 12.7±14.8 6.0±6.3 5.7±4.3 < 0.001
  Median 5 6 3 5
ICU length of stay, days
n 46 24 11 11
  Mean±SD 8.2±10.3 10.1±12.8 7.0±7.5 5.1±4.6 0.83
  Median 4 4.5 4 3
Costs
Total costs
n 428 122 156 150
  Mean±SD, $ 4924.99±7992.57 6698.52±10,365.09 3553.06±6384.27 4909.33±6991.19 0.19
  Median, $ 890.91 851.11 796.32 1203.49
ICU costs (inpatient only)
n 44 24 9 11
  Mean±SD, $ 24,942.71±26,440.44 32,794.05±31,635.47 18,045.19±17,683.24 13,445.92±10,872.39 0.3
  Median, $ 12,425.23 22,077.93 11,042.00 11,028.99
Non-ICU costs (inpatient only)
n 151 45 48 58
  Mean±SD, $ 8985.26±8012.57 10,265.28±10,177.81 7636.34±5898.45 9108.49±7580.18 0.67
  Median, $ 6431.81 6134.54 5794.51 7908.41
Room and board costs (inpatient only)
n 149 45 47 57
  Mean±SD, $ 8039.01±9926.54 13,964.18±13,914.75 5527.58±6966.90 5432.07±5290.97 0.002
  Median, $ 4062.21 7807.86 2973.67 3979.98
Pharmacy costs
n 221 67 71 83
  Mean±SD, $ 858.76±1156.04 1271.59±1505.83 580.84±831.49 806.85±997.70 0.065
  Median, $ 285.21 342.83 162.77 388.31
Central supply costs
n 147 44 43 60
  Mean±SD, $ 981.50±1652.23 1286.69±1880.23 824.59±1717.20 870.15±1406.98 0.025
  Median, $ 251.6 493.35 122.14 350.09

ED = emergency department; ICU = intensive care unit; SD = standard deviation. All costs are in US dollars. *Cost n-values vary by type of cost and group as further clarified in the table. P-values are derived from Kruskal-Wallis test and calculated for mean±SD. Total costs included ICU, room and board, pharmacy, and central supply, but this is not an exhaustive list of departmental costs included in the total cost. Additionally, all costs were winsorized at the 95th percentile (across all age groups, not within each age group).