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. Author manuscript; available in PMC: 2021 Aug 25.
Published in final edited form as: Int J Oncol. 2009 Oct;35(4):797–804. doi: 10.3892/ijo_00000392

Figure 3.

Figure 3.

Effect of Df on BV (%) calculation. (A and B), A MRI images of the mouse brain before and after USPIO administration (215 μmol/kg). (C), Weighting scheme for BV (%) based on pre-USPIO signal (Spre) at different values of Df. At Df = 0, BV = 100% remains unaffected by Spre. When Df > 0, BV (%) value is reduced depending on Spre value. (D-F), BV (%) images calculated at Df = 0, 0.02 and 0.04 from equation [2]. The background is masked to accentuate the brain region but the inset at the bottom left show the original noise which is reduced as a function of Df. High BV (%) values in the background noise and the hypo-intense regions of Spre are attenuated at Df = 0.04. (G-I), Histograms of BV (%) images at Df = 0, 0.02 and 0.04 using BV (%) > 0 within the mouse region. The histograms of BV (%) at Df = 0.02 and 0.04 show gradual increase in frequencies of low BV (%). The contrast between the mouse region and background increases at high Df values.