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. 2021 Jun 27;48(3):277–287. doi: 10.1177/14653125211027266

Table 1.

Characteristics of included studies.

Study Sample Population/type of tooth Index test Target condition/outcome Adjuncts Comments
Charalampakis (2018)
Retrospective cohort
20 Class I patients; 398 teeth, both arches, mostly mild crowding 3 men, 17 women; mean age 36.5 years; range 18.2–79.9 years; canines, premolars and incisors ClinCheck® Rotation following anterior aligner treatment, before refinement
(Also: horizontal/vertical displacement, transverse changes)
No restriction on attachment use/according to doctor’s prescription Anterior Invisalign® (SmartTrack material); superimpositions made on virtual software based on stationary posterior teeth
Grunheid (2017)
Retrospective cohort
30 patients; both arches, ~600 teeth mostly mild crowding 13 men, 17 women; mean age 21.6± 9.8 years; all teeth ClinCheck® Rotation, following Invisalign treatment (also: tipping, torque, translation) Attachment use and IPR as prescribed Invisalign®; superimpositions based on best-fit surface-based registration
Haouili (2020)
Prospective cohort
38 patients; both arches, 899 teeth 13 men, 25 women; included teenage patients; mean age 36 years; all teeth ClinCheck® Rotation, following Invisalign treatment (also: tipping, intrusion, extrusion) Both arches average 6 attachments and <1 mm IPR Invisalign®; superimpositions based on best-fit surface-based registration
Kravitz (2008)
Prospective cohort
31 patients (53 canines: 33 maxillary, 20 mandibular); anterior crowding <5 mm 13 men, 18 women; age > 18 years (mean age 29.4 years); canines. Part of a larger clinical study ClinCheck® Rotation, following anterior aligner treatment 3 groups: attachments only, IPR only, no attachments or IPR Anterior Invisalign®;
superimpositions made on virtual software based on stationary posterior teeth
Kravitz (2009)
Prospective cohort
37 patients (401 maxillary and mandibular incisors and canines); anterior crowding <5 mm 14 men, 23 women; mean age 31 years; canines and incisors ClinCheck® Rotation, following anterior aligner treatment (also: expansion, constriction, intrusion, extrusion, tipping) No restriction on attachment use and IPR; use of IPR in 45% of sample, use of attachments in 17% according to doctor’s prescription Anterior Invisalign®;
superimpositions made on virtual software based on stationary posterior teeth
Lombardo (2017)
Retrospective cohort
16 patients (345 maxillary and mandibular teeth); crowding <5 mm 6 men, 10 women; mean age 28.6 years; all teeth VAM software (Vectra,
Canfield Scientific, Fairfield, NJ, USA)
Rotation following F22 aligner treatment (also: mesiodistal tipping, vestibulolingual tipping) No restriction on attachment use and IPR according to doctor’s prescription F22 aligners; superimpositions based on best-fit 100-reference point registration
Simon (2014)
Retrospective cohort
30 patients (49 teeth, maxillary molars and incisors; maxillary and mandibular premolars) 11 men, 19 women; included teenage patients; mean age 32.9 ±16.3 years; central incisors, premolars, molars ClinCheck® Rotation of premolars following Invisalign treatment (also: molar distalisation, central incisor torque) Subgroups with ± attachment use Invisalign®; superimpositions using a surface matching algorithm

IPR, interproximal reduction.