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. 2021 May 21;70(8):1898–1909. doi: 10.2337/db21-0066

Table 4.

Serum carnitine, acylcarnitines, and acylcarnitine ratios of groups

Control subjects T2D patients with hyperglycemia KPD patients with DKA T1D patients with DKA
N 17 21 52 21
Carnitine (µmol/L) 27.0 ± 1.9 25.0 ± 2.4 14.9 ± 1.7ab 15.1 ± 1.8ab
Acylcarnitine from fatty acids (µmol/L)
 C16 0.072 ± 0.005 0.075 ± 0.009 0.129 ± 0.009ab 0.148 ± 0.018ab
 C14 0.020 ± 0.003 0.019 ± 0.003 0.038 ± 0.005ab 0.055 ± 0.011ab
 C8 0.134 ± 0.019 0.147 ± 0.031 0.228 ± 0.032 0.236 ± 0.040
 C2 6.4 ± 0.46 13.4 ± 2.7 27.2 ± 2.7ab 26.8 ± 2.3ab
Acylcarnitine ratios
 C16-to-C14 ratio 3.9 ± 0.19 4.4 ± 0.32 3.5 ± 0.32 4.3 ± 0.26
 C16-to-C8 ratio 0.67 ± 0.08 0.89 ± 0.16 0.84 ± 0.11 1.01 ± 0.11
 C16-to-C2 ratio 0.012 ± 0.001 0.007 ± 0.001a 0.006 ± 0.001a 0.006 ± 0.001a
 C14-to-C8 ratio 0.182 ± 0.031 0.199 ± 0.028 0.254 ± 0.033 0.266 ± 0.047
 C14-to-C2 ratio 0.003 ± 0.00 0.002 ± 0.000a 0.002 ± 0.000a 0.002 ± 0.000a
 C8-to-C2 ratio 0.022 ± 0.004 0.011 ± 0.001a 0.009 ± 0.001a 0.009 ± 0.001a

Data are means ± SEM. Because data were not normally distributed, nonparametric one-way ANOVA (Kruskal-Wallis test) was performed with post hoc Dunn multiple comparisons.

a

Value significantly different from that of control subjects (P < 0.05).

b

Value significantly different from that of T2D group (P < 0.05).