Table 3.
Univariable and multivariable analyses of factors associated with neurologic complications.
| Factor | Univariable analysis | P -value | Multivariable analysis | P -value | ||
|---|---|---|---|---|---|---|
| OR | 95% CI | OR | 95% CI | |||
| Overall neurologic complications | ||||||
| Age | 1.03 | 1.01–1.05 | 0.003 | |||
| Obesity (BMI ≥ 30) | 2.07 | 1.06–4.05 | 0.034 | |||
| Hypertension | 2.11 | 1.31–3.40 | 0.002 | |||
| Peripheral arterial disease | 2.60 | 1.43–4.75 | 0.002 | |||
| CPR history before ECMO | 2.97 | 1.80–4.89 | <0.001 | |||
| Lowest SBP | 0.89 | 0.86–0.92 | <0.001 | 0.89 | 0.86–0.93 | <0.001 |
| CABG combined with aortic surgery | 6.00 | 1.65–21.76 | 0.006 | 9.22 | 2.10–40.55 | 0.003 |
| ECPR | 3.00 | 1.68–5.36 | <0.001 | |||
| Failure to wean off CPB | 0.57 | 0.36–0.93 | 0.023 | |||
| Brain death | ||||||
| Age | 1.06 | 1.02–1.11 | 0.002 | 1.06 | 1.01–1.12 | 0.022 |
| Obesity (BMI ≥ 30) | 2.78 | 1.12–6.90 | 0.028 | |||
| Peripheral arterial disease | 3.14 | 1.35–7.30 | 0.008 | |||
| CPR history before ECMO | 6.95 | 3.14–15.42 | <0.001 | |||
| Lowest SBP | 0.81 | 0.77–0.86 | <0.001 | 0.81 | 0.76–0.87 | <0.001 |
| CABG | 2.89 | 1.34–6.25 | 0.007 | |||
| ECPR | 3.88 | 1.74–8.63 | 0.001 | |||
| Intracranial hemorrhage | ||||||
| Coagulation disorders | 8.76 | 1.67–45.85 | 0.010 | 9.75 | 1.83–51.89 | 0.008 |
| Atrial fibrillation | 10.00 | 1.02–97.71 | 0.048 | 12.19 | 1.22–121.61 | 0.033 |
| Cerebral infarction | ||||||
| Atrial fibrillation | 8.15 | 1.31–50.62 | 0.024 | |||
| Seizures | ||||||
| Hyperlipidemia | 5.75 | 1.69–19.60 | 0.005 | |||
BMI, body mass index; CABG, coronary artery bypass grafting; CPB, cardiopulmonary bypass; CPR, cardiopulmonary resuscitation; ECMO, extracorporeal membrane oxygenation; ECPR, extracorporeal cardiopulmonary resuscitation; SBP, systolic blood pressure.