Table 2.
Numbers of HSCT in China 2019 by indication, donor type, and stem cell source.
| MSD | HID | URDa | CB | Syngeneic | Autoa | Total | |||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| PB | BM | BM + PB | Unknown | Total | PB | BM | BM + PB | Unknown | Total | ||||||||||||
| PB only | PB + third-party CB | BM only | BM + third-party CB | BM + PB only | BM + PB + third-party CB | PB only | PB + third-party CB | BM only | BM + third-party CB | BM + PB only | BM + PB + third-party CB | ||||||||||
| Myeloid malignancies | 715 | 13 | 1 | 0 | 183 | 4 | 125 | 1041 | 820 | 112 | 24 | 2 | 1430 | 134 | 374 | 2896 | 485 | 196 | 0 | 193 | 4811 |
| AML | 536 | 10 | 129 | 3 | 83 | 761 | 642 | 78 | 11 | 2 | 1113 | 100 | 273 | 2219 | 361 | 158 | 188 | 3687 | |||
| CML | 28 | 6 | 10 | 44 | 37 | 3 | 59 | 3 | 18 | 120 | 16 | 5 | 0 | 185 | |||||||
| MDS | 135 | 3 | 1 | 41 | 1 | 28 | 209 | 129 | 13 | 13 | 232 | 29 | 62 | 478 | 88 | 27 | 5 | 807 | |||
| MDS/MPN | 12 | 4 | 3 | 19 | 7 | 16 | 19 | 2 | 21 | 65 | 19 | 5 | 108 | ||||||||
| MPN | 4 | 3 | 1 | 8 | 5 | 2 | 7 | 14 | 1 | 1 | 24 | ||||||||||
| Lymphoid malignancies | 372 | 5 | 0 | 6 | 109 | 3 | 40 | 535 | 425 | 67 | 4 | 8 | 970 | 77 | 194 | 1745 | 271 | 107 | 2 | 2449 | 5109 |
| ALL | 312 | 2 | 6 | 96 | 2 | 33 | 451 | 352 | 56 | 4 | 7 | 871 | 66 | 160 | 1516 | 229 | 98 | 2 | 50 | 2346 | |
| MM | 6 | 4 | 1 | 1 | 12 | 12 | 12 | 0 | 1112 | 1136 | |||||||||||
| other plasma cell disorders | 2 | 2 | 1 | 1 | 2 | 1 | 69 | 74 | |||||||||||||
| HL | 2 | 2 | 1 | 1 | 1 | 0 | 106 | 110 | |||||||||||||
| NHL | 50 | 3 | 9 | 6 | 68 | 60 | 10 | 1 | 98 | 11 | 34 | 214 | 40 | 9 | 1112 | 1443 | |||||
| Mixed phenotype acute leukemia | 13 | 4 | 5 | 22 | 18 | 3 | 1 | 41 | 9 | 11 | 83 | 7 | 5 | 1 | 118 | ||||||
| Solid tumors | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 2 | 0 | 0 | 0 | 50 | 52 |
| Neuroblastoma | 1 | 1 | 43 | 44 | |||||||||||||||||
| other solid tumors | 1 | 1 | 7 | 8 | |||||||||||||||||
| Nonmalignant disorders | 206 | 6 | 6 | 21 | 143 | 3 | 79 | 464 | 218 | 66 | 16 | 3 | 494 | 68 | 120 | 985 | 445 | 194 | 1 | 1 | 2090 |
| SAA | 124 | 2 | 1 | 92 | 2 | 50 | 271 | 130 | 23 | 14 | 380 | 28 | 73 | 648 | 208 | 125 | 1 | 0 | 1253 | ||
| Other bone marrow failure | 6 | 2 | 8 | 18 | 1 | 2 | 21 | 27 | 8 | 64 | |||||||||||
| Thalassemia | 53 | 3 | 4 | 21 | 49 | 1 | 25 | 156 | 50 | 38 | 2 | 3 | 44 | 19 | 31 | 187 | 165 | 4 | 0 | 512 | |
| Inherited disorders of metabolism | 3 | 3 | 6 | 1 | 6 | 6 | 2 | 21 | 13 | 31 | 68 | ||||||||||
| Primary immune deficiencies | 8 | 1 | 1 | 10 | 4 | 3 | 8 | 14 | 1 | 30 | 18 | 23 | 81 | ||||||||
| Hemophagocytic lymphohistiocytosis | 12 | 1 | 2 | 1 | 16 | 28 | 1 | 38 | 11 | 78 | 14 | 3 | 1 | 112 | |||||||
| others | 15 | 2 | 4 | 21 | 16 | 1 | 36 | 3 | 4 | 60 | 21 | 12 | 29 | 143 | |||||||
| Total | 1321 | 24 | 7 | 27 | 441 | 10 | 253 | 2083 | 1497 | 250 | 45 | 13 | 2972 | 291 | 703 | 5771 | 1229 | 514 | 3 | 2723 | 12,323 |
Not all centers reported stem cell source data, and that is classified as unknown.
a97% of URD and 99% of autologous HSCT used PB as stem cell source, so total number of URD and autologous HSCT are shown in the table.