Figure 9. Representative photomicrograph of a section of the heart tissue section stained with Haematoxylin and Eosin (X 40). A)The control group showing hemorrhage ,interstitial edema, necrosis and Neutrophil infiltration .B) The sham group showing normal architecture C) The vehicle group showing sever hemorrhage and extravasations of RBC, presence of sever interstitial edema, presence of Neutrophil infiltration and necrosis. D) The Berberine pretreated group showing mild cardiac injury with absence of necrosis and few interstitial odema and PMN infilteration.