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. Author manuscript; available in PMC: 2022 Aug 11.
Published in final edited form as: Nano Lett. 2021 Jul 21;21(15):6584–6591. doi: 10.1021/acs.nanolett.1c01973

Figure 3.

Figure 3.

LNP-SNAs effectively deliver mRNA with organ-specific function. (A) Luc mRNA expression in major organs by treatment. Luminescence was detected in harvested organs 6 h after the administration of 0.1 mg kg−1 Luc mRNA. (B, C) LNP-SNAs exhibit organ-specific function in the context of mRNA expression. Luminescence was detected in harvested organs 6 h after the administration of 0.1 mg kg−1 Luc mRNA. (One-tailed student’s t test, * = p < 0.05, each dot represents a biologically independent replicate, with 4–7 biologically independent replicates per treatment).