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Effect of L-citrulline supplementation on hypothalamic mRNA expression of stress-related genes during acute heat stress. (A) Heat shock factor 1 (HSF1). (B) Heat shock factor 3 (HSF3). (C) Heat shock protein 60 (HSP 60). (D) Heat shock protein 70 (HSP 70). (E) Heat shock protein 90 (HSP 70). Data are presented as mean ± SEM (n = 8). TNZ, thermoneutral; HS, heat stress. a,bDifferent letters indicate significant difference of D×E interaction at P < 0.05.
