Table 2.
Association between VEGF haplotypes and breast cancer risk
| Haplotypea | Cases (%) | Controls (%) | OR(95%CI) | p value |
|---|---|---|---|---|
| AICGCC | 31.3 | 23.8 | 1 (Reference) | |
| CDTCCC | 23.7 | 28.9 | 0.56 (0.38–0.81) | 0.003 |
| CDTGCC | 19.6 | 25.6 | 0.63 (0.44–0.92) | 0.018 |
| AICGTC | 9.0 | 9.3 | 0.75 (0.43–1.30) | 0.31 |
| AICGCT | 3.1 | 1.8 | 1.22 (0.40–3.74) | 0.73 |
| AICGTT | 1.8 | 2.0 | 0.76 (0.25–2.33) | 0.64 |
| CDTCCT | 1.7 | 1.2 | 1.25 (0.30–5.19) | 0.76 |
| CDTGCT | 1.4 | 1.5 | 0.65 (0.13–3.35) | 0.61 |
Significant p values are shown in bold
OR odds ratio, CI confidence interval
aIn order of −2578C/A, −2549I/D, −460T/C, +405C/G, −7C/T and +936C/T