FIGURE 4.

FZHFZY regulates the mRNA and protein expression of epidermal differentiation molecules in IMQ-induced psoriatic mice. (A) Total RNA was isolated from skin tissues, and RT-PCR was used to investigate the levels of loricrin, filaggrin, involucrin, keratin 5, keratin 14 and keratin 15. (B) Representative western blot of epidermal differentiation protein in the skin of mice with IMQ-induced psoriasis. (C) Quantification of the amounts of epidermal differentiation protein to β-actin. Data are shown as the mean ± standard error of at least three independent experiments (*p < 0.05, **p < 0.01, ***p < 0.001 vs. IMQ-induced psoriasis group; n = 6).