. Author manuscript; available in PMC: 2022 Sep 1.

Published in final edited form as: FASEB J. 2021 Sep;35(9):e21840. doi: 10.1096/fj.202001616RR

TABLE 3.

Summary of BMEC results.

Outcome Measures		Results	Sex		Age		Treatment
Outcome Measures		Results	Female	Male	Young	Old	Control	BMP-2	TPO
Proliferation		▼▼	X	X		X	X
		▲▲		X	X	X		X	X
		▲▲	X			X		X	X
		▲▲	X		X				X
Vessel-Like Structure Formation		▼▼		X		X	X
		▲▲	X			X	X
		▲▲	X	X		X		X
		▲▲		X	X				X
Migration		▲▲	X	X		X	X
		▼▼	X		X	X		X	X
		▼▼		X	X		X	X	X
RT PCR	CD 31	▲▲		X		X	X
		▼▼	X			X	X
		▲▲		X	X			X
		▼▼	X		X			X
	FLT-1	▼▼	X	X		X	X
		▲▲	X	X		X		X	X
		▲▲		X	X				X
	ANGPT1	▼▼	X			X	X
		▼▼	X		X			X	X
		▼▼		X		X		X	X
		▲▲	X			X			X
	ANGPT2	▼▼	X	X		X	X
		▼▼	X	X	X			X
		▲▲		X		X		X
		▲▲	X	X		X			X
	NTN1	▼▼	X	X		X	X
		▲▲	X		X	X		X
		▼▼		X	X			X
		▲▲	X	X		X			X
		▼▼	X	X	X				X
	ROBO2	▼▼	X	X		X	X
		▲▲	X			X		X
		▼▼		X		X		X	X
		▲▲		X	X				X
	SLIT3	▲▲		X		X	X
		▲▲	X		X	X		X
		▼▼		X	X				X

For the results column, down arrow=decrease, up arrow=increase. An “X” in the sex, age, or treatment columns indicate changes in the outcome measure. For example, the first row demonstrates that proliferation was decreased in both male and female, old, control BMECs, when compared to respective male and female, young BMECs. Similarly shaded rows indicate the same observed pattern of marked (“X”) groups in which the outcome measure was significantly changed.