Table 2.

Ratio of means with 95% CIs of PANSS total scores compared between the four sources of data (individual participant data, clinical study report, journal publication and registry report)

Treatment	IPD vs. CSR	IPD vs. journal publication	IPD vs. registry report	CSR vs. journal publication	CSR vs. registry report	Journal publication vs. registry report
Risperidone	0.87 (− 0.37, 1.48)	0.21 (− 0.05, 0.68)	NA	0.38 (− 0.07, 0.81)	NA	NA
Paliperidone	0.29 (− 0.02, 0.60)	0.11 (− 0.17, 0.87)	0.49 (− 0.66, 1.24)	0.49 (− 0.39, 1.37)	0 (− 0.99, 0.99)	− 0.49 (− 1.75, 0.78)
Paliperidone palmitate	0.11 (− 0.13, 0.29)	0.08 (− 0.17, 0.33)	0.21 (− 0.53, 0.95)	0 (− 0.23, 0.23)	0.13 (− 0.22, 0.48)	0.13 (− 0.25, 0.51)

IPD individual participant data, CSR clinical study report, NA not applicable