Table 1.
Vaccine Type | MOA/effect | Examples |
---|---|---|
mRNA vaccines (Jackson et al., 2020; Polack et al., 2020) | ○ Have the genetic code for the coronavirus ‘spike’ protein made as an “mRNA” and delivered in lipid nanoparticles | Pfizer-BioNTech (Comirnaty) Moderna (Spikevax) |
Non-replicating viral vector vaccines (Sadoff et al., 2021; Folegatti et al., 2020; Logunov et al., 2021) | ○ Have the spike protein genes in a nonreplicating viral vector (commonly from an adenovirus). | AstraZeneca/Oxford (Vaxzevria) Gamaleya Research Institute (Sputnik V) Johnson and Johnson (Janssen COVID-19 vaccine) |
Inactivated virus vaccines (Wang et al., 2020) | ○ Use an inactivated form of the whole coronavirus. | Sinovac (CoronaVac) Sinopharm (Sinopharm CNBG) |
Protein vaccines (Keech et al., 2020) | Contains the full-length spike glycoprotein of the virus plus an adjuvant delivered on the surface of synthetic lipid nanoparticles. | Novavax (NVX-CoV2373) |