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. 2021 Aug 25;56:103225. doi: 10.1016/j.msard.2021.103225

Table 1.

Types of COVID-19 vaccines.

Vaccine Type MOA/effect Examples
mRNA vaccines (Jackson et al., 2020; Polack et al., 2020) ○ Have the genetic code for the coronavirus ‘spike’ protein made as an “mRNA” and delivered in lipid nanoparticles Pfizer-BioNTech (Comirnaty)
Moderna (Spikevax)
Non-replicating viral vector vaccines (Sadoff et al., 2021; Folegatti et al., 2020; Logunov et al., 2021) ○ Have the spike protein genes in a nonreplicating viral vector (commonly from an adenovirus). AstraZeneca/Oxford (Vaxzevria)
Gamaleya Research Institute (Sputnik V)
Johnson and Johnson (Janssen COVID-19 vaccine)
Inactivated virus vaccines (Wang et al., 2020) ○ Use an inactivated form of the whole coronavirus. Sinovac (CoronaVac)
Sinopharm (Sinopharm CNBG)
Protein vaccines (Keech et al., 2020) Contains the full-length spike glycoprotein of the virus plus an adjuvant delivered on the surface of synthetic lipid nanoparticles. Novavax (NVX-CoV2373)