Table 1.
Demographic characteristics.
| Healthy (n=12) | IBS (n=12) | |
|---|---|---|
| Female sex, n (%) | 10 (83.3) | 10 (83.3) |
| Age in years, median [IQR] | 36.78 [30.09 – 47.19] | 45.0 [35.37 – 48.56] |
| BMI in kg/m2, median [IQR] | 21.99 [21.80 – 23.25] | 23.65 [22.65 – 24.57] |
| Current smoking, n (%) | 0 (0) | 4 (33.3) |
| Current alcohol use (<15 units/week), n (%) | 6 (50) | 7 (58.3) |
| Number of fecal samples1, n (%) | ||
| 1 | - | - |
| 2 | - | 1 (8.3) |
| 3 | - | - |
| 4 | 1 (8.3) | - |
| 5 | - | 4 (33.3) |
| 6 | 4 (33.3) | 2 (16.7) |
| 7 | 6 (50.0) | 3 (25.0) |
| 8 | 1 (8.3) | 2 (16.7) |
| GSRS, median [IQR] | ||
| Abdominal Pain | 1.67 [1.08-2.25] | 3.33 [2.00-4.67]$ |
| Regurgitation Syndrome | 1.00 [1.00-1.00] | 2.50 [1.00-3.50]# |
| Diarrhea Syndrome | 1.00 [1.00-1.33] | 3.33 [1.00-1.33]$ |
| Indigestion Syndrome | 1.75 [1.50-2.50] | 4.75 [3.75-5.13]$ |
| Constipation Syndrome | 1.67 [1.00-1.92] | 3.33 [2.33-4.67]$ |
| Medication use, n (%) | ||
| PPI | - | 3 (25) |
| NSAID | - | - |
| Prokinetic | - | - |
| Spasmolytic | - | 2 (16.7) |
| Laxative | - | 1 (8.3) |
| Antidiarrheal | - | - |
| Antibiotic | - | - |
| Probiotic | - | - |
| Prebiotic | - | - |
| Other | 7 (58.3) | 7 (58.3) |
Differences tested using Mann-Whitney U test for continuous data and χ2- or Fisher’s exact test for categorical data. Significances are shown for IBS versus healthy. *p < 0.05; #p < 0.01; $p < 0.001.
1Less than one fecal sample per day was collected in case of absence of bowel movement; more than one fecal sample per day was collected in case of diarrhea.