. Author manuscript; available in PMC: 2021 Dec 1.

Published in final edited form as: Toxicol Appl Pharmacol. 2020 Sep 23;408:115250. doi: 10.1016/j.taap.2020.115250

Table 3.

Effect of PFOS on liver steatosis histopathology

Scores	SD	SD +PFOS	H-SD	H-SD+PFOS	HFD	HFD +PFOS

0	6/8	4/5	7/8	3/6	0/7	0/6
1	2/8	1/5	0/8	1/6	0/7	0/6
2	0/8	0/5	1/8	2/6	3/7	0/6
3	0/8	0/5	0/8	0/6	2/7	1/6
4	0/8	0/5	0/8	0/6	2/7	4/6
5	0/8	0/5	0/8	0/6	0/7	1/6

≥3	0/8 (0%)	0/5 (0%)	0/8 (0%) ^¶	0/6 (0%)	4/7 (57%) ^*	6/6 (100%) ^*

Formalin fixed hepatic tissue sections were stained with hematoxylin and eosin (Fig. 2A). Livers were scored for lipid accumulation (range from 0 to 5, where 0 is the least and 5 is most severe). Statistical analysis was performed using Kruskal–Wallis test followed by Dunn’s multiple comparison test for multiple comparisons. N=5–8/treatment group

indicates p<0.05 versus SD

^¶

indicates p<0.05 for H-SD versus HFD.