(a) Flowchart showing 1,000 GISTs treated surgically at a
single institution[25], of which 150 had
primary tumors and underwent treatment with neoadjuvant imatinib (Neo-IM). Note
that only patients with complete data for response evaluation (n=125) were
analyzed for survival in subsequent figures. (b) Response to Neo-IM
in 150 patients by mRECIST (top), tumor viability (middle), and mitotic rate
after resection (bottom). ‘x’ indicates no evaluable data for that
factor. For mRECIST, viability, and mitotic rate there were 12, 17, and 26
unknown, respectively. Matched vertical lines in each graph represent the same
patient.