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. 2021 Aug 17;9(9):e1226–e1241. doi: 10.1016/S2214-109X(21)00298-9

Table 1.

Preterm births in singleton and multiple pregnancies and in primiparous and multiparous women in China, 2012–18

Year
Change 2012–18 Annual rate of increase (95% CI)*
Total 2012 2013 2014 2015 2016 2017 2018
All pregnancies (n=9 645 646)
Very preterm 73 681 (0·6%) 9079 (0·6%) 9461 (0·6%) 10 755 (0·6%) 9949 (0·7%) 11 569 (0·7%) 11 784 (0·6%) 11 084 (0·7%) 13·3% 1·8% (0·5 to 3·0)
Moderate preterm 92 551 (0·8%) 12 241 (0·8%) 12 326 (0·8%) 13 655 (0·8%) 12 377 (0·8%) 14 068 (0·8%) 14 317 (0.8%) 13 567 (0·8%) 3·8% 0·3% (−0·9 to 1·5)
Late preterm 499 012 (4·7%) 65 047 (4·5%) 63 832 (4·5%) 72 604 (4·5%) 66 294 (4·6%) 77 565 (4·7%) 79 706 (4·8%) 73 964 (4·9%) 8·8% 1·5% (0·9 to 2·2)
All preterm 665 244 (6·1%) 86 367 (5·9%) 85 619 (5·9%) 97 014 (5·9%) 88 620 (6·1%) 10 3202 (6·2%) 10 5807 (6·2%) 98 615 (6·4%) 8·8% 1·3% (0·6 to 2·1)
Singleton pregnancies (n=9 474 961)§
Very preterm 64 058 (0·6%) 7948 (0·5%) 8288 (0.6%) 9270 (0·6%) 8589 (0·6%) 10 092 (0·6%) 10 254 (0·6%) 9617 (0·6%) 13·2% 1·6% (0·4 to 2·9)
Moderate preterm 78 953 (0·7%) 10 524 (0·7%) 10 579 (0·7%) 11 615 (0·7%) 10 535 (0·7%) 12 017 (0·7%) 12 232 (0·7%) 11 451 (0·7%) 2·9% 0 (−1·2 to 1·3)
Late preterm 432 751 (4·1%) 57 284 (4·1%) 55 688 (4·0%) 62 973 (4·0%) 57 342 (4·1%) 67 692 (4·2%) 68 769 (4·2%) 63 003 (4·3%) 6·1% 1·2% (0·5 to 1·8)
All preterm 575 762 (5·4%) 75 756 (5·3%) 74 555 (5·3%) 83 858 (5·3%) 76 466 (5·4%) 89 801 (5·5%) 91 255 (5·5%) 84 071 (5·7%) 6·4% 1·0% (0·4 to 1·7)
Multiple pregnancies (n=170 547)§
Very preterm 9606 (5·1%) 1127 (4·8%) 1164 (4·9%) 1484 (5·3%) 1360 (5·2%) 1476 (5·2%) 1529 (5·1%) 1466 (5·1%) 6·0% 2·5% (1·0 to 4·0)
Moderate preterm 13 588 (7·2%) 1710 (7·2%) 1747 (7·2%) 2038 (7·3%) 1841 (7·1%) 2051 (7·4%) 2085 (7·1%) 2116 (7·4%) 3·1% 1·8% (0·3 to 3·4)
Late preterm 66 245 (37·1%) 7762 (34·8%) 8141 (35·5%) 9629 (36·2%) 8951 (36·3%) 9872 (37·2%) 10 933 (38·9%) 10 957 (40·1%) 15·2% 2·4% (1·6 to 3·2)
All preterm 89 439 (49·4%) 10 599 (46·8%) 11052 (47·5%) 13 151 (48·8%) 12 152 (48·5%) 13 399 (49·8%) 14 547 (51·1%) 14 539 (52·7%) 12·4% 1·9% (1·2 to 2·6)
Primiparous women (n=5 440 535)
Very preterm 37 851 (0·6%) 5295 (0·5%) 5481 (0·6%) 5891 (0·6%) 5243 (0·6%) 5728 (0·6%) 5293 (0·6%) 4920 (0·6%) 18·5% 2·9% (1·2 to 4·7)
Moderate preterm 48 866 (0·8%) 7476 (0·8%) 7314 (0·8%) 7770 (0·8%) 6607 (0·8%) 7117 (0·8%) 6529 (0·8%) 6053 (0·8%) 5·3% 0·7% (−1·3 to 2·8)
Late preterm 270 558 (4·5%) 41 472 (4·4%) 39 194 (4·4%) 42 709 (4·4%) 36 321 (4.6%) 40 023 (4·6%) 36 609 (4·7%) 34 230 (4·8%) 9·1% 1·7% (0·9 to 2·4)
All preterm 357 275 (5·9%) 54 243 (5·7%) 51 989 (5·7%) 56 370 (5·7%) 48 171 (6.0%) 52 868 (6·0%) 48 431 (6·1%) 45 203 (6·2%) 9·3% 1·6% (0·7 to 2·6)
Multiparous women (n=4 194 100)
Very preterm 35 145 (0·7%) 3774 (0·7%) 3973 (0·7%) 4855 (0·7%) 4699 (0.7%) 5837 (0·7%) 6298 (0·6%) 5709 (0·7%) −5·7% −1·6% (−3·1 to −0·1)
Moderate preterm 430 86 (0·8%) 4755 (0·9%) 5005 (0·9%) 5877 (0·9%) 5766 (0·8%) 6943 (0·8%) 7629 (0.8%) 7111 (0·8%) −5·7% −1·7% (−3·1 to −0·2)
Late preterm 226 805 (4·8%) 23 515 (4·7%) 24 618 (4·7%) 29 868 (4·7%) 29 955 (4·7%) 37 523 (4·8%) 42 648 (4·8%) 38 678 (4·9%) 4·4% 0·6% (−0·2 to 1·5)
All preterm 305 036 (6·3%) 32 044 (6·3%) 33 596 (6·3%) 40 600 (6·3%) 40 420 (6·3%) 50 303 (6·3%) 56 575 (6·2%) 51 498 (6·4%) 1·9% 0·1% (−0·8 to 1·0)

Data are n (%), unless otherwise stated. % represents the number of liveborn preterm deliveries per 100 deliveries, adjusting for the sampling distribution of the population. Annual rate of increase represents the annual rate change in preterm birth rate from 2012 to 2018. Very preterm babies were born after 28–31 completed weeks' gestation. Moderate preterm babies were born after 32–33 weeks' gestation. Late preterm babies were born after 34–36 weeks' gestation.

*

Estimated by Poisson regression model with robust standard error.

Adjusted for the sampling distribution of the population.

Adjusted for the clustering of births within hospitals.

§

The records of 138 (<0·1%) pregnancies did not contain information regarding the number of fetuses.

A total of 11 011 (0·1%) women did not report information on parity.