TABLE 3.

Predominant fecal bacterial phyla and genera present in healthy adults before and after consuming BB-12-containing interventions in a crossover study

Phylum and genus	% of sequencesa
	Baseline	YS	POST	PRE	CAP	Final washout	SEM	P value
Firmicutes	82	82	80	79	82	79	0.76	0.58
Blautia	8.4	8.3	7.9	6.8	8.2	7.3	0.35	0.77
Faecalibacterium	5.2	6.3	5.4	6.4	6.2	6.9	0.34	0.69
Ruminococcus	4.9	4.1	5.4	5.4	5.7	5.3	0.33	0.78
Coprococcus	2.7	3.3	3.3	2.8	3.1	3.1	0.13	0.74
Roseburia	1.7	1.8	1.8	1.4	2.0	2.6	0.19	0.62
Lachnospira	1.2	1.8	2.1	1.5	1.6	1.7	0.13	0.21
Dialister	1.0	1.1	1.1	1.3	1.4	0.8	0.12	0.77
Dorea	1.0	1.1	0.89	0.67	1.0	0.9	0.05	0.20
Streptococcus	0.59 AB	1.04 A	0.89 AB	0.73 AB	0.45 B	0.38 B	0.06	0.01
Clostridium	0.56	0.77	0.55	0.57	0.70	0.81	0.06	0.76
Oscillospira	0.83	0.51	0.61	0.69	0.57	0.56	0.05	0.46
Enterococcus	0.40	0.40	0.41	0.42	0.35	0.37	0.02	0.81
Lactobacillus	0.22	0.29	0.30	0.32	0.48	0.64	0.07	0.54
Lachnobacterium	0.29	0.28	0.08	0.47	0.19	0.33	0.07	0.72
Anaerostipes	0.23	0.18	0.22	0.23	0.31	0.20	0.02	0.65
Turicibacter	0.21	0.17	0.13	0.08	0.12	0.24	0.02	0.45
Megasphaera	0.08	0.07	0.10	0.21	0.10	0.13	0.03	0.79
Bacteroidetes	12	13	14	14	12	14	0.64	0.81
Bacteroides	8.3	8.9	9.9	9.2	7.9	10.3	0.53	0.81
Parabacteroides	0.92	1.0	1.1	1.0	1.0	1.1	0.08	0.96
Prevotella	0.44	0.46	0.38	0.81	0.28	0.28	0.14	0.91
Actinobacteria	3.7	2.8	3.6	4.4	3.7	3.7	0.36	0.72
Bifidobacterium	3.5	2.6	3.3	4.2	3.4	3.5	0.36	0.71
Collinsella	0.11	0.12	0.11	0.12	0.13	0.14	0.01	0.96
Proteobacteria	1.5	1.7	1.5	1.8	1.3	1.5	0.08	0.49
Sutterella	0.22	0.30	0.27	0.42	0.30	0.40	0.03	0.34
Citrobacter	0.22	0.20	0.21	0.37	0.22	0.24	0.03	0.32
Haemophilus	0.13	0.23	0.10	0.12	0.05	0.14	0.03	0.64
Verrucomicrobia	0.19	0.11	0.24	0.18	0.15	0.36	0.03	0.94
Akkermansia	0.19	0.11	0.24	0.18	0.15	0.36	0.00	0.41

^aValues are presented as means with pooled SEMs (n = 147). Values in a row without a common letter are significantly different (P < 0.05).