FIG 6.

Genome similarities to the Escherichia coli ST131 S65EC genomic islands. Rings drawn by BRIG show the presence of these regions among 11 C2 (“deep sky blue” rings), 22 C2-subset (red rings), and 18 international virotype E strains (yellow and “aquamarine” rings). Colored segments indicate >70% similarity, and gray segments indicate >50% similarity by BLAST comparison between the regions of interest and each genome. The GI-pheU harboring cnf1/hlyCABD gens were detected among all except one C2-subset strain, which was negative for the mentioned virulence genes (virotype F), and also international genomes. The prophage 8 (Phi8) region was completely found in one C2 (EC274) and one international strain (ERR161303), and prophage 2 (Phi2) was partially detected among all except one international strain (ERR161303). The last ring (blue ring) indicates EC958 strain.