TABLE 2.
Difference in mean IgG antibody concentration obtained from dried blood spots, comparing baseline (day 0 samples stored at central laboratory) with samples stored for 30 days at sites
Antibody and IDa | Day 0 meanb |
Dibrugarh |
Chennai |
Jaipur |
Ghatampur |
||||
---|---|---|---|---|---|---|---|---|---|
Mean differencec |
P valued | Mean difference |
P value | Mean difference |
P value | Mean difference |
P value | ||
Measles | |||||||||
1 | 95.7 | −3.8 | 0.59 | −3.7 | 0.61 | −10.8 | 0.14 | −13.6 | 0.10 |
2 | 345.8 | −2.0 | 0.87 | −26.3 | 0.06 | −24.5 | 0.04 | −24.5 | 0.07 |
3 | 437.5 | 153.1 | <0.001 | 2.9 | 0.80 | −95.0 | <0.001 | −92.2 | <0.001 |
4 | 3,986.9 | 182.8 | 0.31 | 40.3 | 0.80 | −647.6 | 0.001 | −641.5 | 0.001 |
5 | 1,917.0 | −62.3 | 0.47 | −123.9 | 0.12 | −715.18 | <0.001 | −560.6 | <0.001 |
6 | 3,445.9 | −104.6 | 0.33 | −150.8 | 0.12 | −297.3 | 0.03 | −229.6 | 0.05 |
Rubella | |||||||||
1 | 64.6 | 1.3 | 0.86 | −16.0 | 0.02 | −13.3 | 0.06 | −19.2 | 0.01 |
2 | 5.3 | −0.7 | 0.03 | −0.9 | 0.001 | −0.2 | 0.46 | −0.0 | 0.92 |
3 | 46.7 | 16.4 | <0.001 | −4.6 | 0.02 | −11.9 | <0.001 | −12 | <0.001 |
4 | 161.0 | 4.2 | 0.27 | 5.0 | 0.23 | −28.5 | <0.001 | −26.7 | <0.001 |
5 | 19.8 | 5.0 | <0.001 | −2.2 | 0.05 | −6.1 | <0.001 | −6.1 | <0.001 |
6 | 169.1 | −18.4 | <0.001 | −18.1 | <0.001 | −31.3 | <0.001 | −23.8 | <0.001 |
ID, identifier.
D0, day 0.
Mean difference calculated as day 30 site value minus day 0 value calculated as the mean across the nine replicates for each individual.
P values obtained from one-way analysis of variance test. Boldface values show P < 0.002 (Bonferroni-corrected P value accounting for 24 pairwise comparisons).