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. 2021 Aug 4;6(4):e00592-21. doi: 10.1128/mSphere.00592-21

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Copyright © 2021 Hirabayashi et al.

This is an open-access article distributed under the terms of the Creative Commons Attribution 4.0 International license.

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FIG 1 — (Upper panel) Circular representation of a 240.5-kbp IncC-IncX3 hybrid plasmid, pNUITM-VK5_mdr, cocarrying multiple antimicrobial resistance genes including bla_NDM-4, tet(X), and tmexCD3-toprJ3 in K. aerogenes NUITM-VK5 isolated in Vietnam in 2021. (Lower panel) Linear comparison of tmexCD3-toprJ3-containing regions in K. aerogenes pNUITM-VK5_mdr and in a chromosome of P. mirabilis RFG134-1 isolated in China in 2019. Red, yellow, cyan, green, gray, and black indicate carbapenem and tetracycline resistance genes (CRG/TRG), other AMR genes (ARG), mobile gene elements (MGE), type IV secretion system (T4SS)-associated genes involved in conjugation, other coding sequences (Other), and GC content, respectively. The blue color in comparison of sequences indicates almost 100% identity.