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. 2021 Aug 11;6(4):e00647-21. doi: 10.1128/mSphere.00647-21

FIG 5.

FIG 5

(A) Virus neutralization assay assessing clinical SARS-CoV-2 isolate SARS-CoV-2/human/Eng/2-20 infection of Vero E6 cells in the presence of purified IgG from human basigin-immunized rabbits (black). All values are relative to a virus-only control (dotted line at y = 100). Each point indicates the mean, and error bars show standard deviations of triplicate measurement. The negative control was purified IgG from rabbits vaccinated with S antigen (red). The positive control was the published inhibitory anti-spike MAb 1B10 (blue) (B) (Left) P. falciparum assay of growth inhibition activity (GIA) showing the functionality of the purified IgG from basigin-immunized rabbits, where each point is the mean of a triplicate. (Right) Purified IgG prior to immunization with basigin, tested for GIA at 10 mg/ml (n = 2). The bar indicates the mean, and the error bar shows the standard deviation.