FIG 2.

All CoPS species contain the vwb gene. Maximum likelihood phylogenetic tree of 50 staphylococcal species and 5 additional subspecies based on a core genome alignment of 231 concatenated genes. A list of the genome sequences used is included in Table S2. Coagulase-positive species are highlighted in bold, and coagulase-variable species are highlighted with an asterisk. Species containing the vwb gene are represented with orange branches, with orange circles indicating the branch on which this gene was acquired. Red circles indicate the nodes in which additional vwb copies were acquired. The single acquisition event of the coa gene by an ancestor of the S. aureus complex is indicated by a green circle. Genome locations of the vwb and coa genes in each CoPS lineage are represented by colored bars on a blue ring depicting the chromosome. Support values are shown on each branch and were calculated using the Shimodaira-Hasegawa test. The Mammaliicoccus cluster is the root of the tree.