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Staphylococcal vWbp has an evolutionary history distinct from that of coagulase. (A) Unrooted maximum-likelihood tree constructed using FastTree v2 of the Coa and vWbp protein sequences. Each of the main clusters is highlighted and labeled. Coagulase positivity has evolved on multiple occasions through acquisition of vwb followed by evolution according to species. (B) Phylogenetic reconstruction of the non-aureus CoPS based on vWbp protein sequences.
