Table 5. Univariable and multivariable HRs of EC cancer-specific death by the four age-at-diagnosis groups.

Age at diagnosis	N	Events	5-year CSS	Model 1a	Model 2b	Model 3c	Model 4d	Model5e	Model6f
				HR (95% CI)	HR (95% CI)	HR (95% CI)	HR (95% CI)	HR (95% CI)	HR (95% CI)
≤50	227	4	97.6%	0.407(0.144-1.146)	0.457(0.159-1.310)	0.428(0.149-1.229)	0.423(0.147-1.215)	0.421(0.146-1.210)	0.250(0.058-1.069)
51-65	675	20	96.8%	0.559(0.296-1.057)	0.546(0.286-1.043)	0.589(0.306-1.133)	0.591(0.307-1.136)	0.566(0.293-1.092)	0.705(0.333-1.491)
66-70	65	5	90.6%	2.509(0.978-6.433)	2.074 (0.801-5.373)	2.101(0.811-5.447)	2.091 (0.807-5.420)	2.157(0.832-5.592)	1.621(0.474-5.549)
>70	57	9	81.9%	5.516(2.61-11.66)	5.015(2.264-11.11)	4.469(1.980-10.09)	4.618(2.038-10.46)	5.334(2.324--12.24)	5.821(2.296-14.76)

^aModel 1 Univariate and unadjusted for age groups. ^bModel 2 Adjusted for age, MI, LVSI, LUSI, CSI, grade, and pathology. ^cModel 3 Adjusted for the same variables as in Model 2, plus additionally surgical type. ^dModel 4 Adjusted for the same variable as in Model 3, plus additionally EBRT±VBT. ^eModel 5 Adjusted for the same variable as in Model 4, plus additionally chemotherapy. ^fModel 6 Adjusted for the same variable as in Model 5, plus additionally treatment-related late toxicity.