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. 2021 Aug 10;13(15):19272–19281. doi: 10.18632/aging.203251

Figure 5.

Figure 5

ANRIL increases resistance of pancreatic cancer cells to gemcitabine chemotherapy. (A) MTT assay showed that overexpression of ANRIL resisted the inhibition of pancreatic cancer cells by gemcitabine, but miR-181a mimics reversed the effect which caused by ANRIL. OD value reflected the relative proliferative activity of each group. (B) Colony formation assays suggested the effects of miR-181a, ANRIL and gemcitabine on the proliferation of PANC-1 cells and BxPC-3 cells. *P < 0.05, **P < 0.01, ***P < 0.001.