Table 6.
Univariate and multivariate analyses of the association of different variables with RFS.
| Variable | Univariate | Multivariate | ||
|---|---|---|---|---|
| HR (95% CI) | P | HR (95% CI) | P | |
| Clinical stage | 3.413 (2.307-5.050) | <0.001 | 6.396 (3.514 -11.641) | <0.001 |
| Histology | 1.207 (0.655-2.222) | 0.547 | ||
| Grade | 1.335 (0.500-3.566) | 0.564 | ||
| Lymph node | 4.487 (2.316-8.693) | <0.001 | 4.689 (3.090-9.663) | 0.006 |
| PMN stromal density | 1.964 (1.012-3.811) | 0.046 | 0.793 (0.371-1.695) | 0.550 |
| NET stromal density | 2.523 (1.307-4.873) | 0.006 | 2.655 (1.212-5.818) | 0.015 |
CI, confidence interval; HR, hazard ratio; NET, neutrophil extracellular trap; PMN, polymorphonuclear neutrophil; RFS, recurrence-free survival.