Table 2.
Decreased FA content in kidney of rubcnF/F-TSKO mice.
| CTRL |
TSKO |
|||||
|---|---|---|---|---|---|---|
| Lipid | Mean | SD | Mean | SD | TSKO:CTRL | P value |
| FA (14:0) | 1.5 | 0.9 | 0.8 | 0.6 | 0.53 | 0.150 |
| FA (16:0) | 111.8 | 19.0 | 79.8 | 22.3 | 0.71 | 0.032 |
| FA (16:1) | 28.0 | 7.2 | 21.5 | 3.2 | 0.77 | 0.076 |
| FA (18:0) | 69.3 | 14.1 | 45.1 | 15.0 | 0.65 | 0.023 |
| FA (18:1) | 205.2 | 35.9 | 154.1 | 20.9 | 0.75 | 0.016 |
| FA (18:2) | 202.0 | 29.7 | 151.5 | 27.8 | 0.75 | 0.017 |
| FA (18:3) | 9.3 | 2.1 | 6.9 | 1.9 | 0.74 | 0.077 |
| FA (20:2) | 9.1 | 1.5 | 6.4 | 1.1 | 0.70 | 0.006 |
| FA (20:3) | 9.8 | 2.0 | 6.5 | 1.0 | 0.66 | 0.005 |
| FA (20:4) | 54.6 | 13.6 | 33.7 | 3.1 | 0.62 | 0.025 |
| FA (20:5) | 5.1 | 1.0 | 3.9 | 0.8 | 0.76 | 0.047 |
| FA (22:1) | 2.1 | 0.3 | 1.3 | 0.2 | 0.63 | 0.001 |
| FA (22:2) | 0.7 | 0.1 | 0.5 | 0.1 | 0.74 | 0.022 |
| FA (22:5) | 14.4 | 3.0 | 10.7 | 2.2 | 0.74 | 0.044 |
| FA (22:6) | 44.7 | 14.1 | 29.0 | 7.7 | 0.65 | 0.043 |
| FA total | 767.5 | 113.9 | 551.5 | 101.2 | 0.72 | 0.009 |
Difference in FA contents of the whole kidneys from 12-month-old RubcnF/F-CTRL and rubcnF/F-TSKO mice was analyzed by lipidomic analysis. Mean value and SD of each FA contents (pmol/mg kidney weight), the ratio of the levels of rubcnF/F-TSKO to RubcnF/F-CTRL mice, and P value vs. RubcnF/F-CTRL mice are indicated. n = 5 or 6 in each group.